Description

Description:
Retatrutide is a long-acting synthetic peptide designed as a tri-agonist of the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors. This multifunctional receptor profile makes Retatrutide a significant research tool for studying complex metabolic regulation, energy expenditure, and glucose homeostasis. Structural modifications enhance its plasma stability and receptor affinity, enabling extended bioactivity in controlled experimental settings.

Research Applications:
Retatrutide is commonly employed in preclinical and in vitro investigations involving:

• Tri-agonist interactions with GLP-1, GIP, and glucagon receptors
• Mechanistic studies of glucose metabolism and insulin signaling
• Research on lipid utilization and thermogenic energy pathways
• Evaluation of peptide engineering for enhanced receptor specificity and duration of action

Molecular Formula: C331H512N94O99
Molecular Weight: ≈ 7476 g/mol
Sequence: H-His-Aib-Gln-Asp-Phe-Thr-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-NH₂
(Contains proprietary lipidation and amino-acid substitutions for stability)

Form: Lyophilized powder
Purity: ≥ 98 % (HPLC)
Storage: Store at –20 °C. Avoid repeated freeze–thaw cycles.
Solubility: Soluble in sterile water or aqueous buffer

Handling and Use:
This compound is supplied exclusively for in vitro laboratory research. It is not for human consumption, diagnostic, or veterinary purposes. Use appropriate protective laboratory procedures and sterile technique when handling all research materials.